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Anti-infection

Antibiotic Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HCV Protease HIV HIV Integrase HIV Protease HSV Influenza Virus Orthopoxvirus Parasite TMV Reverse Transcriptase RSV SARS-CoV Virus Protease
Apoptosis

Apoptosis Bcl-2 Family Caspase c-Myc Ferroptosis FKBP IAP Family MDM-2/p53 PKD Necroptosis Pyroptosis RIP kinase Thymidylate Synthase TNF Receptor TRADD Cuproptosis
Autophagy

Autophagy FKBP LRRK2 Mitophagy OGA ULK
Cell Cycle/DNA Damage

Antifolate APC ATM/ATR Aurora Kinase BMI-1 Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA/RNA Synthesis DNA-PK Early 2 Factor (E2F) Eukaryotic Initiation Factor (eIF) GAK G-quadruplex HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 DNA Stain Nucleoside Antimetabolite/Analog Nur77 p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 Cyclin G-associated Kinase (GAK) ROCK ATF6 Haspin Kinase Sirtuin SRPK PDI Telomerase TOPK Topoisomerase Wee1
Cytoskeletal Signaling

Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK ROCK
Endocrinology/Hormones

Adrenergic Receptor Androgen Receptor Angiotensin-converting Enzyme (ACE) Aromatase Cholecystokinin Receptor TSH Receptor Estrogen Receptor/ERR GHSR Glucocorticoid Receptor GNRH Receptor Mineralocorticoid Receptor Opioid Receptor PGD synthase PGE synthase Progesterone Receptor Thyroid Hormone Receptor
Epigenetics

AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase MicroRNA PARP PKC Protein Arginine Deiminase Methionine Adenosyltransferase (MAT) Sirtuin JAK
GPCR/G Protein

5-HT Receptor Adenosine Receptor Adenylate Cyclase (AC) Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR TSH Receptor Neuropeptide Y Receptor Dopamine Receptor EBI2/GPR183 Endothelin Receptor Formyl peptide receptor (FPR) GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPR109A GPR119 GPR139 GPR27 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR Melanocortin Receptor Melatonin Receptor mGluR Neurokinin Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor PKG Prostaglandin Receptor Protease-Activated Receptor (PAR) Apelin Receptor (APJ) Ras GPR88 Free Fatty Acid Receptor E3 Ligase Ligand-Linker Conjugates RGS GPR4 Secretin Receptor Mas-related G-protein-coupled Receptor (MRGPR) GPR35 GPR52 MCHR1 (GPR24) Leukotriene Receptor GLP Receptor Somatostatin Receptor Arrestin Platelet-activating Factor Receptor (PAFR) Mas-related G-protein-coupled Receptor (MRGPR) Kisspeptin Receptor G Protein-coupled Receptor Kinase (GRK) G protein-coupled Bile Acid Receptor 1 Succinate Receptor 1 Protease Activated Receptor (PAR) Vasopressin Receptor

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Reverse Transcriptase

Reverse Transcriptase相关产品（37）

货号	产品名	中文名称	产品描述
SJ-MX3596	Lersivirine		Lersivirine is a non-nucleoside, next generation reverse transcriptase inhibitor (IC50 = 118 nM for the wild-type HIV-1 enzyme). It inhibits a panel of 14 single-point mutant HIV-1 reverse transcriptases with mean IC50 values within 10-fold of the wild-type enzyme. Lersivirine inhibits HIV-1 virus replication in MT-2 cells with EC50 values of 5.04, 13.1, and 34.9 nM at multiplicities of infection (MOIs) of 0.005, 0.05, and 0.5, respectively, and displays synergistic or additive effects when used in combination with a variety of antiretroviral agents.
SJ-MA0069D	Tenofovir hydrate	替诺福韦水合物	Tenofovir hydrate (GS 1278 hydrate) 是一种核苷酸逆转录酶 (nucleotide reverse transcriptase) 抑制剂，可用于 HIV和慢性乙型肝炎 (Hepatitis B; HBV) 的研究。
SJ-MX2576	Dapivirine	达匹维林	Dapivirine (TMC120) 是二芳基嘧啶 (DAPY) 的原型，是具有口服活性的非核苷类逆转录酶抑制剂 (NRTI)。Dapivirine (TMC120) 可直接与 HIV 的逆转录酶结合。Dapivirine (TMC120)调节自噬并诱导 Akt、Bad 和 SAPK/JNK 的激活。
SJ-MA0069E	Tenofovir Disoproxil	替诺福韦酯	Tenofovir Disoproxil (Bis(POC)-PMPA) 是核苷酸逆转录酶抑制剂 (nucleotide reverse transcriptase inhibitor)，有潜力用于艾滋病和慢性乙型肝炎的研究。
SJ-MA0144A	Abacavir sulfate	硫酸阿巴卡韦	Abacavir sulfate 是一个核苷类似物，是一个可以血脑屏障的、竞争性的、逆转录酶抑制剂(NRTI)，可以抑制HIV复制，可以用作抗逆转录病毒药物。
SJ-MA0324	Adefovir	阿德福韦	Adefovir (formerly known as PMEA and GS-0393; trade names Preveon and Hepsera) is a potent DNA polymerase inhibitor with the potential for the treatment of HBV infection.
SJ-MA0420	Pyridoxal phosphate	磷酸吡哆醛	Pyridoxyl phosphate is a purinergic P2 receptor antagonist potentially for the treatment of tardive dyskinesia
SJ-MX3783	AG 555		AG 555 (Tyrphostin AG 555) 是一种有效的抗逆转录病毒药物，是一种有效的选择性 EGFR 抑制剂，可阻断Cdk2 活化。
SJ-MA0443	Zalcitabine		Zalcitabine is a nucleoside analog reverse transcriptase inhibitor (NRTI).
SJ-MA0142	Doravirine (MK-1439)	多拉维林	Doravirine (MK-1439) 是一种高度特异性的 HIV-1 非核苷逆转录酶抑制剂，对野生型以及 K103N 和 Y181C 逆转录酶突变体的 IC50 值分别为 4.5 nM，5.5 nM 和 6.1 nM。
SJ-MA0144	Abacavir	阿巴卡韦	Abacavir 是一个核苷类似物，是一个可以血脑屏障的、竞争性的、逆转录酶抑制剂(NRTI)，可以抑制HIV复制，可以用作抗逆转录病毒药物。
SJ-MA0162	R-10015		R-10015 是一种用于 HIV 感染的广谱抗病毒化合物，是高效选择性的 LIMK 抑制剂，通过结合 ATP 结合口袋阻断 LIMK，抑制人 LIMK1 的 IC50 值为 38 nM。
SJ-MN0347	Corilagin	柯里拉京	Corilagin是一种鞣酸，抑制RNA肿瘤病毒逆转录酶的活性。Corilagin抑制金黄色葡萄球菌的生长，MIC为25μg/mL。Corilagin对肝癌和卵巢癌具有良好的抗肿瘤活性，而对正常细胞和组织的毒性很低。
SJ-MA0163	Etravirine	依曲韦林	Etravirine 是一种非核苷逆转录酶抑制剂 (NNRTI)，具有抗 HIV 的作用。
SJ-MA0178	Didanosine	去羟肌苷	Didanosine(Videx)是逆转录酶抑制剂，IC50为490nM。
SJ-MA0557	Azvudine
SJ-MA0557A	Azvudine hydrochloride
SJ-MA0420A	Pyridoxal hydrochloride	盐酸吡哆醛	Pyridoxal hydrochloride 是一种内源性代谢产物。
SJ-MX6284A	Zinc acetate dihydrate		Zinc acetate dihydrate (Acetic acid zinc salt dihydrate, Dicarbomethoxyzinc dihydrate) 通过靶向逆转录酶的锌促进杀菌剂凝胶的抗病毒活性。
SJ-MA0111	Delavirdine mesylate	地拉韦啶甲磺酸盐	Delavirdine (U 90152) mesylate 是一种有效的口服活性非核苷逆转录酶抑制剂 (NNRTI)。Delavirdine mesylate 选择性地抑制 HIV-1 逆转录酶 (HIV-1 RT) (IC50=0.26 μM)，选择性超过 DNA 聚合酶α (IC50=440 μM) 和 DNA聚合酶 δ (IC50>550 μM)。Delavirdine mesylate 是 HIV-1 病毒复制的抑制剂，可以用于艾滋病的相关研究。