您当前的位置：

信号通路

Anti-infection

Antibiotic Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HCV Protease HIV HIV Integrase HIV Protease HSV Influenza Virus Orthopoxvirus Parasite TMV Reverse Transcriptase RSV SARS-CoV Virus Protease
Apoptosis

Apoptosis Bcl-2 Family Caspase c-Myc Ferroptosis FKBP IAP Family MDM-2/p53 PKD Necroptosis Pyroptosis RIP kinase Thymidylate Synthase TNF Receptor TRADD
Autophagy

Autophagy FKBP LRRK2 Mitophagy OGA ULK
Cell Cycle/DNA Damage

Antifolate APC ATM/ATR Aurora Kinase BMI-1 Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA/RNA Synthesis DNA-PK Early 2 Factor (E2F) Eukaryotic Initiation Factor (eIF) GAK G-quadruplex HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 DNA Stain Nucleoside Antimetabolite/Analog Nur77 p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 Cyclin G-associated Kinase (GAK) Nucleoside Antimetabolite/AnalogOrthopoxvirus ROCK ATF6 Haspin Kinase Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeletal Signaling

Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK ROCK
Endocrinology/Hormones

Adrenergic Receptor Androgen Receptor Angiotensin-converting Enzyme (ACE) Aromatase Cholecystokinin Receptor TSH Receptor Estrogen Receptor/ERR GHSR Glucocorticoid Receptor GNRH Receptor Mineralocorticoid Receptor Opioid Receptor PGD synthase PGE synthase Progesterone Receptor Thyroid Hormone Receptor
Epigenetics

AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain FTO HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase MicroRNA PARP PKC Protein Arginine Deiminase Methionine Adenosyltransferase (MAT) Sirtuin
GPCR/G Protein

5-HT Receptor Adenosine Receptor Adenylate Cyclase (AC) Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR TSH Receptor Neuropeptide Y Receptor Dopamine Receptor EBI2/GPR183 Endothelin Receptor Formyl peptide receptor (FPR) GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR27 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR Melanocortin Receptor Melatonin Receptor mGluR Neurokinin Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor PKG Prostaglandin Receptor Protease-Activated Receptor (PAR) Apelin Receptor (APJ) Ras GPR88 Free Fatty Acid Receptor E3 Ligase Ligand-Linker Conjugates RGS GPR4 Secretin Receptor Mas-related G-protein-coupled Receptor (MRGPR) GPR35 GPR52 MCHR1 (GPR24) Leukotriene Receptor GLP Receptor Somatostatin Receptor Vasopressin Receptor

-收起全部分类

Oxytocin Receptor

Oxytocin Receptor相关产品（25）

货号	产品名	中文名称	产品描述
SJ-BP0060	Carbetocin	卡贝缩宫素	Carbetocin 是一种合成的长效催产素8肽类似物，其临床和药理特性与天然产生的催产素一种催产素 (OT) 类似。Carbetocin 是催产素受体 (oxytocin receptor) 激动剂，Ki 是 7.1 nM。Carbetocin 对催产素受体的嵌合 N 末端 (E1) 具有高亲和力 (Ki=1.17 μM)。Carbetocin 具有用于产后出血研究的潜力。Carbetocin 能透过血脑屏障，可以通过激活 CNS 中的催产素受体而具有类抗抑郁活性。
SJ-MX3330	Encenicline hydrochloride		Encenicline (EVP-6124; MT-4666) hydrochloride is a novel partial agonist of α7 nicotinic acetylcholine receptor. EVP-6124 enhances dopamine, acetylcholine, and glutamate efflux in rat cortex and nucleus accumbens. EVP-6124 improves memory performance by potentiating the acetylcholine response of α7 nicotinic acetylcholine receptors.
SJ-BP0081	Oxytocin	催产素;缩宫素	Oxytocin 是一种九氨基酸肽，在下丘脑神经元中合成，并沿垂体后叶轴突向下转运，分泌到血液中。Oxytocin可以诱导类似抗应激的作用，例如降低血压和皮质醇水平。它提高了疼痛阈值，发挥抗焦虑作用并刺激各种积极的社会互动。此外，Oxytocin促进生长和愈合。反复接触Oxytocin会通过影响其他递质系统的活动而产生长期影响，这种模式使Oxytocin具有潜在的临床意义。
SJ-MX2665	PNU-120596		PNU-120596 (PNU120596; NSC 216666; PNU 120596; NSC-216666) is a potent and selective PAM (positive allosteric modulator) of α7 nAChR (acetylcholine receptor) with an EC50 of 216 NM.
SJ-MX1564B	Varenicline hydrochloride		Varenicline hydrochloride是α4β2烟碱受体的部分激动剂,用于戒烟。
SJ-MX4129	Sofiniclin		Sofiniclin (ABT 894) 是 nAChR 的激动剂，作为注意力缺陷症的潜在的非刺激性研究。
SJ-MX3330A	Encenicline		Encenicline (EVP-6124) 是α7烟碱型乙酰胆碱受体（nAChRs）的部分激动剂，在体内外显现出高亲和力。
SJ-MX3859	PNU-282987 S enantiomer free base		PNU-282987 S enantiomer free base是PNU-282987的S型对映体。PNU-282987是一种α7烟碱乙酰胆碱受体（α7 nAChR）激动剂。
SJ-MX3975	NS 1738		NS 1738 (NSC 213859) is a novel and potent positive allosteric modulator of the α7 nAChR, with respect to positive modulation of nicotinic alpha7 receptor (α7 nAChR) with EC50 of 3.4 μM in oocyte experiments.
SJ-MX4268	LIT-001		LIT-001 is a non-peptide, potent and specific agonist of the oxytocin receptor (EC50 value of 25 nM at human OTR). First nonpeptide OT receptor agonist active in an animal model of autism spectrum disorders (ASD) after peripheral ip administration.
SJ-MX4351	nAChR agonist 1		nAChR agonist 1 是一种有效的、脑通透性强的、口服有效的 α7 烟碱乙酰胆碱受体 (α7 nicotinic acetylcholine receptor) 的正向变构调节剂。nAChR agonist 1 在 Ca2+ 中，对内源性表达 α7 nAChR 的人 IMR-32 神经母细胞瘤细胞的 EC50 为 0.32 μM。nAChR agonist 1 可用于阿尔茨海默病的研究。
SJ-MX4711	L-371,257		L-371,257 是一种口服生物有效的，不能透过血脑屏障的，竞争性的，选择性催产素受体拮抗剂 (pA2=8.4)，对催产素受体 (Ki=19 nM) 和血管加压素 V1a 受体 (vasopressin V1a receptor，Ki=3.7 nM) 具有高亲和力。
SJ-MX4729	Methyllycaconitine citrate	甲基牛扁亭柠檬酸盐	Methyllycaconitine citrate 是 α7 神经元烟碱型乙酰胆碱受体 (α7nAChR) 的特异性拮抗剂。
SJ-MA0381	Dinotefuran	呋虫胺	Dinotefuran is an insecticide of the neonicotinoid class developed by Mitsui Chemicals for control of insect pests such as aphids, whiteflies, thrips, leafhoppers, leafminers, sawflies, mole cricket, white grubs, lacebugs, billbugs, beetles, mealybugs, and cockroaches on leafy vegetables, in residential and commercial buildings, and for professional turf management. Its mechanism of action involves disruption of the insect's nervous system by inhibiting nicotinic acetylcholine receptors.
SJ-MN0817	(+)-Sparteine	(+)-鹰爪豆碱	(+)-Sparteine 是一种天然生物碱，作为一种神经节阻滞剂。在神经细胞中，(+)-Sparteine 竞争性地抑制烟碱型乙酰胆碱受体 (nACh receptor) 活性。
SJ-BP0052	Atosiban	阿托西班	Atosiban is a novel and potent oxytocin and vasopressin antagonist.
SJ-MX4416	Rocuronium Bromide	罗库溴铵	Rocuronium Bromide is an aminosteroid non-depolarizing neuromuscular blocker.
SJ-MX1564A	Varenicline		Varenicline,一种合成的酒石酸盐,是α4β2烟碱型乙酰胆碱受体的部分激动剂.Varenicline对α4β2烟碱型乙酰胆碱受体的亲和力(0.15 nM)显著高于对其它烟碱型乙酰胆碱受体亚型的亲和力.Varenicline结合后可阻止烟碱占据受体,从而抑制烟碱诱导的多巴胺能激活。
SJ-MN0893	Hirsuteine	去氢毛钩藤碱	Hirsuteine is an indole alkaloid extracted from Uncaria genus. Hirsuteine non-competitively antagonizes nicotine-mediated dopamine release by blocking ion permeation through nicotinic receptor channel complexes.
SJ-MX4231	CCMI		CCMI (AVL-3288) 是一种有效、选择性的 α7 nAChR 正向别构调节剂，不是通过正性结合位点与 α7 nAChR 结合并使其激活，能有效正向调节 α7 nAChR 上激动剂诱导的电流。CCMI 在神经系统认知功能紊乱疾病中具有潜在疗效。