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GPR55

GPR55相关产品(2)
货号 产品名 中文名称 产品描述
SJ-MX3621 CID 16020046 CID 16020046 (CID-16020046) is a novel, potent and selective GPR55 (LPI receptor) antagonist / inverse agonist which inhibits GPR55 constitutive activity with IC50 of 0.15 uM. GPR55 is a G protein-coupled receptor that is weakly activated by some cannabinoids at nM concentrations. CID16020046 has been shown to block GPR55-mediated endothelial wound healing and reverse LPI-inhibited platelet aggregation. The G protein-coupled receptor 55 (GPR55) is a lysophosphatidylinositol (LPI) receptor that is also responsive to certain cannabinoids. Although GPR55 has been implicated in several (patho)physiologic functions, its role remains enigmatic owing mainly to the lack of selective GPR55 antagonists.
SJ-MX2110 AM251 AM251是选择性大麻素1 (CB1) 受体拮抗剂,IC50 为8 nM。AM251也是 GPR55 的激动剂,EC50为39 nM。