您当前的位置：

信号通路

Anti-infection

Antibiotic Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HCV Protease HIV HIV Integrase HIV Protease HSV Influenza Virus Orthopoxvirus Parasite TMV Reverse Transcriptase RSV SARS-CoV Virus Protease
Apoptosis

Apoptosis Bcl-2 Family Caspase c-Myc Ferroptosis FKBP IAP Family MDM-2/p53 PKD Necroptosis Pyroptosis RIP kinase Thymidylate Synthase TNF Receptor TRADD
Autophagy

Autophagy FKBP LRRK2 Mitophagy OGA ULK
Cell Cycle/DNA Damage

Antifolate APC ATM/ATR Aurora Kinase BMI-1 Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA/RNA Synthesis DNA-PK Early 2 Factor (E2F) Eukaryotic Initiation Factor (eIF) GAK G-quadruplex HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 DNA Stain Nucleoside Antimetabolite/Analog Nur77 p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 Cyclin G-associated Kinase (GAK) Nucleoside Antimetabolite/AnalogOrthopoxvirus ROCK ATF6 Haspin Kinase Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeletal Signaling

Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK ROCK
Endocrinology/Hormones

Adrenergic Receptor Androgen Receptor Angiotensin-converting Enzyme (ACE) Aromatase Cholecystokinin Receptor TSH Receptor Estrogen Receptor/ERR GHSR Glucocorticoid Receptor GNRH Receptor Mineralocorticoid Receptor Opioid Receptor PGD synthase PGE synthase Progesterone Receptor Thyroid Hormone Receptor
Epigenetics

AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain FTO HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase MicroRNA PARP PKC Protein Arginine Deiminase Methionine Adenosyltransferase (MAT) Sirtuin
GPCR/G Protein

5-HT Receptor Adenosine Receptor Adenylate Cyclase (AC) Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR TSH Receptor Neuropeptide Y Receptor Dopamine Receptor EBI2/GPR183 Endothelin Receptor Formyl peptide receptor (FPR) GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR27 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR Melanocortin Receptor Melatonin Receptor mGluR Neurokinin Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor PKG Prostaglandin Receptor Protease-Activated Receptor (PAR) Apelin Receptor (APJ) Ras GPR88 Free Fatty Acid Receptor E3 Ligase Ligand-Linker Conjugates RGS GPR4 Secretin Receptor Mas-related G-protein-coupled Receptor (MRGPR) GPR35 GPR52 MCHR1 (GPR24) Leukotriene Receptor GLP Receptor Somatostatin Receptor Vasopressin Receptor

-收起全部分类

Myosin

Myosin相关产品（8）

全部 Myosin调节剂(1) Myosin抑制剂(4) Myosin激活剂(1)

货号	产品名	中文名称	产品描述
SJ-MX0816	Mavacamten (MYK-461)		Mavacamten (MYK-461, SAR439152)是具有口服活性的心肌肌球蛋白（cardiac myosin）的小分子调节剂，其在牛心脏和人心脏中的 IC50 值分别为 490，711 nM。Mavacamten (MYK-461)通过降低心肌肌球蛋白重链的ATP酶活性（小鼠心肌肌原纤维的IC50值为0.3μM）来抑制调节肥厚型心肌病的肌节过强收缩。肌节收缩抑制剂可能是治疗肥厚型心肌病（HCM）的一种有价值的方法。
SJ-MX0119	(-)-Blebbistatin	布雷他汀	(-)-Blebbistatin ((S)-(-)-Blebbistatin) 是一种细胞渗透性抑制剂，是肌球蛋白II（myosin II） ATP酶活性的选择性抑制剂，不抑制肌球蛋白轻链激酶 (MLCK)，抑制卵裂沟的缢缩，不干扰有丝分裂或收缩环的组装。
SJ-MX0925	ML-7 hydrochloride		ML-7 hydrochloride 是一种萘磺酰胺衍生物，有效抑制 MLCK (IC50=300 nM)。ML-7 hydrochloride 也是一种 YAP/TAZ 抑制剂。
SJ-MX0685	Omecamtiv mecarbil		Omecamtiv mecarbil (CK-1827452) 是一种心脏特异性的肌球蛋白 (cardiac myosin) 激活剂。
SJ-MX4025	Aficamten		Aficamten (CK-3773274;CK-274) is a Next-Generation Cardiac Myosin Inhibitor for the Treatment of Hypertrophic Cardiomyopathy.
SJ-MX2543	BTS	N-苄基-对甲苯磺酸胺	BTS (N-Benzyl-p-toluenesulfonamide) 是一种有效和选择性的骨骼肌肌球蛋白 II 亚片段 1 (S1) ATPase 活性抑制剂，对肌动蛋白和 Ca²⁺ 刺激的肌球蛋白 S1 ATPase 的 IC50 值约为 5 µM。BTS 可特异性抑制骨骼肌快速纤维的收缩。
SJ-MX4778	HA-100
SJ-MX5304	ML-9