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Anti-infection

Antibiotic Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HCV Protease HIV HIV Integrase HIV Protease HSV Influenza Virus Orthopoxvirus Parasite TMV Reverse Transcriptase RSV SARS-CoV Virus Protease
Apoptosis

Apoptosis Bcl-2 Family Caspase c-Myc Ferroptosis FKBP IAP Family MDM-2/p53 PKD Necroptosis Pyroptosis RIP kinase Thymidylate Synthase TNF Receptor TRADD
Autophagy

Autophagy FKBP LRRK2 Mitophagy OGA ULK
Cell Cycle/DNA Damage

Antifolate APC ATM/ATR Aurora Kinase BMI-1 Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA/RNA Synthesis DNA-PK Early 2 Factor (E2F) Eukaryotic Initiation Factor (eIF) GAK G-quadruplex HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 DNA Stain Nucleoside Antimetabolite/Analog Nur77 p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 Cyclin G-associated Kinase (GAK) Nucleoside Antimetabolite/AnalogOrthopoxvirus ROCK ATF6 Haspin Kinase Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeletal Signaling

Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK ROCK
Endocrinology/Hormones

Adrenergic Receptor Androgen Receptor Angiotensin-converting Enzyme (ACE) Aromatase Cholecystokinin Receptor TSH Receptor Estrogen Receptor/ERR GHSR Glucocorticoid Receptor GNRH Receptor Mineralocorticoid Receptor Opioid Receptor PGD synthase PGE synthase Progesterone Receptor Thyroid Hormone Receptor
Epigenetics

AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain FTO HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase MicroRNA PARP PKC Protein Arginine Deiminase Methionine Adenosyltransferase (MAT) Sirtuin
GPCR/G Protein

5-HT Receptor Adenosine Receptor Adenylate Cyclase (AC) Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR TSH Receptor Neuropeptide Y Receptor Dopamine Receptor EBI2/GPR183 Endothelin Receptor Formyl peptide receptor (FPR) GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR27 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR Melanocortin Receptor Melatonin Receptor mGluR Neurokinin Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor PKG Prostaglandin Receptor Protease-Activated Receptor (PAR) Apelin Receptor (APJ) Ras GPR88 Free Fatty Acid Receptor E3 Ligase Ligand-Linker Conjugates RGS GPR4 Secretin Receptor Mas-related G-protein-coupled Receptor (MRGPR) GPR35 GPR52 MCHR1 (GPR24) Leukotriene Receptor GLP Receptor Somatostatin Receptor Vasopressin Receptor

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Dopamine Receptor

Dopamine Receptor相关产品（97）

货号	产品名	中文名称	产品描述
SJ-MM0031	MPTP hydrochloride		MPTP hydrochloride可透过血脑屏障的多巴胺 (dopamine) 神经毒素，通过杀死大脑黑质中的某些神经元而导致帕金森病的永久性症状，可用于帕金森病相关研究的工具化合物。MPTP hydrochloride 是 MPP⁺ 的前体，可以诱导凋亡 (apoptosis) 作用。
SJ-MX2987	cis-(Z)-Flupentixol dihydrochloride		cis-(Z)-Flupentixol dihydrochloride 是有效、选择性的多巴胺DA D1/D2 受体的拮抗剂，其对D2 受体和 5-HT2A 的 Ki 值分别为 0.38 nM 和 7 nM。
SJ-MX3784	Veralipride	维拉必利	Veralipride is a benzamide neuroleptic medicine indicated in the treatment of vasomotor symptoms associated with the menopause.
SJ-MX2562	Clebopride malate	苹果酸氯波必利	Clebopride malate is a dopamine antagonist drug with antiemetic and prokinetic properties used to treat functional gastrointestinal disorders.
SJ-MX4373	Fluphenazine dihydrochloride	盐酸氟奋乃静	Fluphenazine dihydrochloride（Prolixin）是多巴胺受体 D1DR 和 D2DR 抑制剂。它能够抑制组胺H1受体。
SJ-MX1489	Itopride hydrochloride	盐酸伊托必利	Itopride hydrochloride (HSR803) 是一种促胃动力的 Benzamide (HY-Z0283) 衍生物。Itopride hydrochloride 是一种乙酰胆碱酯酶 (AChE) 和多巴胺受体 D2 (D2DR) 抑制剂。
SJ-MX1493	Brexpiprazole	依匹哌唑	Brexiprazole(OPC-34712)，一种非典型抗精神病药，是人5-HT1A和多巴胺受体的部分激动剂，Ki分别为0.12nM和0.3 nM。Brexpiprazole也是5-HT2A受体的拮抗剂，Ki为0.47 nM。
SJ-MX1499	Perospirone hydrochloride	盐酸哌罗匹隆	Perospirone hydrochloride (SM-9018) 是具有口服活性的 5-HT2A 受体 (Ki 为 0.6 nM) 和多巴胺 D2 受体 (Ki 为 1.4 nM) 的拮抗剂，也是 5-HT1A 受体 (Ki 为 2.9 nM) 的部分激动剂。Perospirone hydrochloride 是一种非典型的抗精神病剂，可用于精神分裂症的研究。
SJ-MX1518	Promazine hydrochloride	盐酸丙嗪	Promazine (Romtiazin) hydrochloride是一种抗精神病药和多巴胺受体 (D2) 拮抗剂。Promazine hydrochloride 抑制多巴胺能神经传递。
SJ-MX1619	ONC206		ONC206是ONC201的一个类似物。ONC206是多巴胺D2-样受体(DRD2/3/4)的选择性拮抗剂，其拮抗作用在纳摩尔级别。ONC206具有广谱的抗肿瘤作用。
SJ-MX1369	Tribenzagan Hydrochloride	盐酸曲美苄胺	Trimethobenzamide hydrochloride 是多巴胺 D2 受体阻断剂，可用作预防恶心和呕吐的止吐剂。
SJ-MX1400A	Quetiapine hemifumarate	富马酸喹硫平	Quetiapine hemifumarate 是一种 5-HT 受体激动剂，对人 5-HT1A 的 pEC50 值为 4.77。Quetiapine hemifumarate 是多巴胺受体 (dopamine receptor) 拮抗剂，对人 D2 的 pIC50 值为 6.33。Quetiapine hemifumarate 对人 D2，HT1A，5-HT2A，5-HT2C 受体具有中高等亲和力，pKi 值为 7.25，5.74，7.54，5.55。具有抗抑郁和抗焦虑作用。
SJ-MX2371	Triflupromazine hydrochloride	盐酸三氟丙嗪	Triflupromazine hydrochloride is a member of a class of drugs called phenthiazines, which are dopamine D1/D2 receptor antagonists.Triflupromazine hydrochloride binds to the dopamine D1 and dopamine D2 receptors and inhibits their activity. Used as an antipsychotic drug.
SJ-MX2501	Alizapride hydrochloride	盐酸阿立必利	Alizapride hydrochloride (Limican; Plitican; Vergentan; Superan; Alizaprida; Litican; MS-5080), the hydrochloride salt of alizapride which is a medication used for the theropy of nausea and vomiting, is a potent dopamine receptor antagonist with prokinetic and antiemetic effects.
SJ-MX2541	Bromocriptine mesylate	甲磺酸溴隐亭	Bromocriptine mesylate 是一种有效的多巴胺 D2/D3 受体激动剂，结合多巴胺 D2 受体，pKi 为 8.05±0.2。
SJ-MX2608	Fenoldopam mesylate	非诺多泮甲磺酸盐	Fenoldopam mesylate (SKF-82526) is a synthetic benzazepine analog acting as a selective D1 receptor partial agonist. Since fenoldopam is the only intravenous agent that improves renal perfusion, in theory it could be beneficial in hypertensive patients with concomitant renal insufficiency.
SJ-MX2639	Levosulpiride	左舒必利	Levosulpiride (RV 12309; RV-12309; S-(-)-Sulpiride) is the S-enantiomer of sulpiride, which is a potent and selective antagonist for D2 dopamine receptors used as an antipsychotic and prokinetic agent. Levosulpiride is a substituted benzamide antipsychotic, reported to be a selective antagonist of dopamine D2 receptor activity on both central and peripheral levels. It is an atypical neuroleptic and a prokinetic agent. Levosulpiride is also claimed to have mood elevating properties.
SJ-MX3295	Tetrahydropalmatine	延胡索乙素	Tetrahydropalmatine 可用于缓解疼痛的研究。Tetrahydropalmatine 通过抑制大鼠杏仁核的多巴胺释放来抑制癫痫发作。
SJ-MN1199	L-Stepholidine	左旋千金藤啶碱	L-Stepholidine (Stepholidine)，一种从中草药 Stephania intermedia 提取的生物碱，是已知的第一种同时具有多巴胺受体 D1 (dopamine D1 receptor) 激动剂和多巴胺受体 D2 (dopamine D2 receptor) 拮抗剂。L-Stepholidine 具有神经保护作用，并抑制海洛因诱导的恢复。L-Stepholidine 是研究阿片成瘾的一种潜在试剂。
SJ-MX2847	Chlorprothixene	氯普噻吨	Chlorprothixene (Cloxan, Taractan, Truxal) is a typical antipsychotic drug of the thioxanthene class and was the first of the series to be synthesized.