货号 | 产品名 | 中文名称 | 产品描述 |
---|---|---|---|
SJ-MX4313 | 4-CMTB | (±)-4-CMTB is a positive allosteric modulator of free fatty acid receptor 2 (FFAR2/GPR43). It selectively induces ERK1/2 phosphorylation in 293 T-REx cells expressing human FFAR2, but not FFAR1 or FFAR3. | |
SJ-MX4171 | TUG-1375 | TUG-1375 is a potent free fatty acid receptor 2 (FFA2/GPR43) agonist with a pKi value of 6.69. TUG-1375 has high solubility, high chemical, microsomal, and hepatocyte stability, and favorable pharmacokinetic properties and was confirmed to induce human neutrophil mobilization and to inhibit lipolysis in murine adipocytes. |