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Anti-infection

Antibiotic Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HCV Protease HIV HIV Integrase HIV Protease HSV Influenza Virus Orthopoxvirus Parasite TMV Reverse Transcriptase RSV SARS-CoV Virus Protease
Apoptosis

Apoptosis Bcl-2 Family Caspase c-Myc Ferroptosis FKBP IAP Family MDM-2/p53 PKD Necroptosis Pyroptosis RIP kinase Thymidylate Synthase TNF Receptor TRADD Cuproptosis
Autophagy

Autophagy FKBP LRRK2 Mitophagy OGA ULK
Cell Cycle/DNA Damage

Antifolate APC ATM/ATR Aurora Kinase BMI-1 Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA/RNA Synthesis DNA-PK Early 2 Factor (E2F) Eukaryotic Initiation Factor (eIF) GAK G-quadruplex HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 DNA Stain Nucleoside Antimetabolite/Analog Nur77 p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 Cyclin G-associated Kinase (GAK) ROCK ATF6 Haspin Kinase Sirtuin SRPK PDI Telomerase TOPK Topoisomerase Wee1
Cytoskeletal Signaling

Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK ROCK
Endocrinology/Hormones

Adrenergic Receptor Androgen Receptor Angiotensin-converting Enzyme (ACE) Aromatase Cholecystokinin Receptor TSH Receptor Estrogen Receptor/ERR GHSR Glucocorticoid Receptor GNRH Receptor Mineralocorticoid Receptor Opioid Receptor PGD synthase PGE synthase Progesterone Receptor Thyroid Hormone Receptor
Epigenetics

AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase MicroRNA PARP PKC Protein Arginine Deiminase Methionine Adenosyltransferase (MAT) Sirtuin JAK
GPCR/G Protein

5-HT Receptor Adenosine Receptor Adenylate Cyclase (AC) Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR TSH Receptor Neuropeptide Y Receptor Dopamine Receptor EBI2/GPR183 Endothelin Receptor Formyl peptide receptor (FPR) GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPR109A GPR119 GPR139 GPR27 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR Melanocortin Receptor Melatonin Receptor mGluR Neurokinin Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor PKG Prostaglandin Receptor Protease-Activated Receptor (PAR) Apelin Receptor (APJ) Ras GPR88 Free Fatty Acid Receptor E3 Ligase Ligand-Linker Conjugates RGS GPR4 Secretin Receptor Mas-related G-protein-coupled Receptor (MRGPR) GPR35 GPR52 MCHR1 (GPR24) Leukotriene Receptor GLP Receptor Somatostatin Receptor Arrestin Platelet-activating Factor Receptor (PAFR) Mas-related G-protein-coupled Receptor (MRGPR) Kisspeptin Receptor G Protein-coupled Receptor Kinase (GRK) G protein-coupled Bile Acid Receptor 1 Succinate Receptor 1 Protease Activated Receptor (PAR) Vasopressin Receptor

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Angiotensin-converting Enzyme (ACE)

Angiotensin-converting Enzyme (ACE)相关产品（26）

货号	产品名	中文名称	产品描述
SJ-MX1927B	Enalaprilat	依那普利拉	Enalaprilat (MK-422 anhydrous) 是口服前体 Enalapril 的活性代谢物，是一种有效，竞争性和长效的血管紧张素转换酶 (ACE) 抑制剂，IC50 值为 1.94 nM。Enalaprilat 可用于高血压的研究。
SJ-MX1927C	Enalapril	依那普利	Enalapril (MK-421) 是一种血管紧张素转换酶 (ACE) 抑制剂，可用于高血压疾病的研究。
SJ-MX2945	Temocapril hydrochloride	盐酸替莫普利	Temocapril hydrochloride 是一种具有口服活性的长效血管紧张素转化酶 (ACE) 抑制剂。Temocapril hydrochloride 可以用于高血压、充血性心力衰竭、急性心肌梗死、胰岛素抵抗和肾脏疾病的研究。
SJ-MX3328	Zofenopril calcium	佐芬普利钙	Zofenopril Calcium (SQ26991) 是抗氧化剂和血管紧张素转化酶 (ACE) 抑制剂。Zofenopril Calcium可以保护心脏，有助于降低高血压。
SJ-MX3779	Omapatrilat		Omapatrilat (also known as BMS-186716) is a novel antihypertensive agent that acts as a potent dual inhibitor of the metalloproteases ACE (angiotensin converting enzyme) and NEP (neutral endopeptidase) with Ki values of 0.64 and 0.45 nM, respectively. Omapatrilat has antihypertensive activity. NEP inhibition results in elevated natriuretic peptide levels, promoting natriuresis, diuresis, vasodilation, and reductions in preload and ventricular remodeling. The drug was promoted for possible uses in congestive heart failure.
SJ-MX2496	Alacepril		Alacepril (Cetapril; DU-1219) 是一种具有长效抗高血压作用的口服活性血管紧张素转换酶 (ACE) 抑制剂，通常用作降压药。
SJ-BP0189	Lisinopril	赖诺普利	Lisinopril (MK-521; MK521; Zestril; Linopril; Lisipril) is a potent angiotensin-converting enzyme (ACE) inhibitor approved for use in treatment of hypertension, congestive heart failure, and heart attacks, and also in preventing renal and retinal complications of diabetes. Lisinopril significantly reduces left ventricular (LV) end-diastolic pressure (EDP), pulmonary capillary wedge pressure (PCWP) and end-diastolic stress, addition of atenolol to Lisinopril further reduces EDP and PCWP. Lisinopril is a structural homologue of enalaprilat, differing only in the second amino acid side chain.
SJ-MX1927A	Enalapril maleate	马来酸依那普利	Enalapril (MK-421) maleate 是血管紧张素转化酶（ACE）抑制剂，用于治疗高血压，糖尿病肾病以及慢性心力衰竭。
SJ-MX2556	Fosinopril sodium	福辛普利钠	Fosinopril (sodium) 是血管紧张素转换酶（ACE）抑制剂的原药，IC50 为 0.18 μM，Ki 值为 1.675 μM。在体内， Fosinopril 在胃肠道黏膜和肝脏中迅速水解为 fosinoprilat。 Fosinopril (sodium)可作用于高血压和慢性心力衰竭。
SJ-MX2832	Quinapril hydrochloride		Quinapril (hydrochloride) (CI-906) 是血管紧张素转化酶 (ACE) 抑制剂的原药。
SJ-MX2837	Benazepril hydrochloride	盐酸贝那普利	Benazepril hydrochloride是血管紧张素转化酶（ACE）抑制剂，可作用于高血压。
SJ-MX2838	Benazepril	贝那普利	Benazepril 是血管紧张素转化酶（ACE）抑制剂，可作用于高血压。
SJ-MX3326	Captopril (SQ 14225)	卡托普利	Captopril (SQ 14225) 是一种含巯基的口服活性血管紧张素转换酶 (ACE) 抑制剂，IC50=0.025 μM。Captopril 也是 NDM-1 抑制剂，IC50 值为 7.9 μM。Captopril 广泛应用于高血压和充血性心力衰竭的研究。Captopril 被证明可通过诱发细胞凋亡而影响细胞生长，进而发挥抗癌活性。
SJ-MX3359	Perindopril erbumine	培哚普利叔丁胺	Perindopril erbumine (Perindopril tert-butylamine salt) 是一种长效的、脑通透性的血管紧张素转换酶(ACE)抑制剂(IC50 = 1.05 nM)。不同于其他ACE抑制剂，它通过抑制VEGF水平抑制肝癌细胞的肿瘤生长，也在体外抑制血管紧张素 II 的产生。
SJ-MX3412	Imidapril hydrochloride	盐酸咪达普利	Imidapril hydrochloride is a prodrug for the active metabolite imidaprilat, an angiotensin-converting enzyme (ACE) inhibitor that suppresses the conversion of angiotensin I to angiotensin II (IC50 = 2.6 nM), thereby preventing vasoconstriction and decreasing aldosterone secretion by the adrenal cortex which leads to an increase in sodium excretion and subsequently increases water outflow.
SJ-MX3937	Delapril hydrochloride		Delapril hydrochloride 是一种血管紧张素转化酶 (ACE) 抑制剂，可用于心血管疾病的研究。
SJ-MX4490	Cilazapril monohydrate		Cilazapril monohydrate is a pyridazine angiotensin-converting enzyme inhibitor (ACE inhibitor) used for the treatment of hypertension and congestive heart failure. It is a prodrug that is hydrolyzed after absorption to its main metabolite cilazaprilat.
SJ-MX4491	Trandolapril		Trandolapril (RU-44570), an antihypertensive drug, is an oral and nonsulfhydryl prodrug that has to be hydrolysed to the active diacid Trandolaprilat. It is a potent ACE inhibitor used to treat high blood pressure.
SJ-MX4492	Ramipril	雷米普利	Ramipril is a non-peptide, angiotensin converting enzyme (ACE) inhibitor (IC50 = 5 nM). A prodrug that is hydrolyzed in vivo to the active metabolite ramiprilat. Displays protective effects on endothelium against high-glucose induced dysfunction. Displays antihypertensive effects.
SJ-MX4494	Moexipril hydrochloride	盐酸莫西普利	Moexipril hydrochloride is a prodrug of the long-acting angiotensin converting enzyme (ACE) inhibitor moexiprilat (IC50s = 2.1 nM and 2.7 µM for moexiprilat and moexipril, respectively). Moexipril hydrochloride has been identified as a phosphodiesterase 4 inhibitor (IC50 = 38 µM for the PDE4B2 isoform) that increases cAMP in cells.