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Anti-infection

Antibiotic Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HCV Protease HIV HIV Integrase HIV Protease HSV Influenza Virus Orthopoxvirus Parasite TMV Reverse Transcriptase RSV SARS-CoV Virus Protease
Apoptosis

Apoptosis Bcl-2 Family Caspase c-Myc Ferroptosis FKBP IAP Family MDM-2/p53 PKD Necroptosis Pyroptosis RIP kinase Thymidylate Synthase TNF Receptor TRADD
Autophagy

Autophagy FKBP LRRK2 Mitophagy OGA ULK
Cell Cycle/DNA Damage

Antifolate APC ATM/ATR Aurora Kinase BMI-1 Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA/RNA Synthesis DNA-PK Early 2 Factor (E2F) Eukaryotic Initiation Factor (eIF) GAK G-quadruplex HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 DNA Stain Nucleoside Antimetabolite/Analog Nur77 p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 Cyclin G-associated Kinase (GAK) Nucleoside Antimetabolite/AnalogOrthopoxvirus ROCK ATF6 Haspin Kinase Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeletal Signaling

Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK ROCK
Endocrinology/Hormones

Adrenergic Receptor Androgen Receptor Angiotensin-converting Enzyme (ACE) Aromatase Cholecystokinin Receptor TSH Receptor Estrogen Receptor/ERR GHSR Glucocorticoid Receptor GNRH Receptor Mineralocorticoid Receptor Opioid Receptor PGD synthase PGE synthase Progesterone Receptor Thyroid Hormone Receptor
Epigenetics

AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain FTO HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase MicroRNA PARP PKC Protein Arginine Deiminase Methionine Adenosyltransferase (MAT) Sirtuin
GPCR/G Protein

5-HT Receptor Adenosine Receptor Adenylate Cyclase (AC) Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR TSH Receptor Neuropeptide Y Receptor Dopamine Receptor EBI2/GPR183 Endothelin Receptor Formyl peptide receptor (FPR) GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR27 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR Melanocortin Receptor Melatonin Receptor mGluR Neurokinin Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor PKG Prostaglandin Receptor Protease-Activated Receptor (PAR) Apelin Receptor (APJ) Ras GPR88 Free Fatty Acid Receptor E3 Ligase Ligand-Linker Conjugates RGS GPR4 Secretin Receptor Mas-related G-protein-coupled Receptor (MRGPR) GPR35 GPR52 MCHR1 (GPR24) Leukotriene Receptor GLP Receptor Somatostatin Receptor Vasopressin Receptor

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GPR40

GPR40相关产品（6）

货号	产品名	中文名称	产品描述
SJ-MX2878	Fasiglifam		Fasiglifam (also known as TAK-875) is a novel, long-acting, selective and orally bioavailable and selective GPR40 agonist with EC50 of 14 nM in human GPR40 expressing CHO cell line, it is 400-fold more potent than oleic acid. TAK-875 has a favorable pharmacokinetic profile which enables long-acting drug efficacy. TAK-875 exhibited potent agonistic activity and high binding affinity to the human GPR40 receptor. In addition, TAK-875 showed excellent agonist potency and selectivity for GPR40 receptor over other members of the FFA receptor family (e.g. EC50>10 μM for others).
SJ-MX2782	GW9508		GW9508 is a potent and selective agonist for the free fatty acid receptor FFA1 (GPR40).
SJ-MN1202	Vincamine	长春胺	Vincamine 是从马达加斯加长春花中提取的一种单萜类吲哚生物碱。Vincamine 可以作为一种外周血管扩张剂 (Vasodilator)，对脑微血管循环有选择性的血管调节作用。Vincamine 是一种 GPR40 激动剂，通过改善β细胞功能障碍和促进葡萄糖刺激型胰岛素分泌 (GSIS) 发挥β细胞保护作用。Vincamine 可改善体内葡萄糖稳态，对 2 型糖尿病 (T2DM) 的研究具有潜力。
SJ-MX1702	Fasiglifam (TAK-875)		Fasiglifam (TAK-875)是一种选择性GPR40激动剂，在表达人GPR40的CHO细胞系中EC50为14 nM，比油酸有效400倍。
SJ-MX1182	DC260126		DC260126 是一种有效的 GPR40 (FFAR1) 拮抗剂。DC260126 剂量依赖性地抑制亚油酸、油酸、棕榈油酸和月桂酸刺激的 GPR40 介导的 Ca2+ 升高 (IC50 分别 6.28， 5.96， 7.07， 4.58 μM)。DC260126 对棕榈酸酯诱导的内质网应激和凋亡 (apoptosis) 有保护作用。
SJ-MX5656	Fezagepras sodium