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Anti-infection

Antibiotic Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HCV Protease HIV HIV Integrase HIV Protease HSV Influenza Virus Orthopoxvirus Parasite TMV Reverse Transcriptase RSV SARS-CoV Virus Protease
Apoptosis

Apoptosis Bcl-2 Family Caspase c-Myc Ferroptosis FKBP IAP Family MDM-2/p53 PKD Necroptosis Pyroptosis RIP kinase Thymidylate Synthase TNF Receptor TRADD Cuproptosis
Autophagy

Autophagy FKBP LRRK2 Mitophagy OGA ULK
Cell Cycle/DNA Damage

Antifolate APC ATM/ATR Aurora Kinase BMI-1 Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA/RNA Synthesis DNA-PK Early 2 Factor (E2F) Eukaryotic Initiation Factor (eIF) GAK G-quadruplex HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 DNA Stain Nucleoside Antimetabolite/Analog Nur77 p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 Cyclin G-associated Kinase (GAK) ROCK ATF6 Haspin Kinase Sirtuin SRPK PDI Telomerase TOPK Topoisomerase Wee1
Cytoskeletal Signaling

Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK ROCK
Endocrinology/Hormones

Adrenergic Receptor Androgen Receptor Angiotensin-converting Enzyme (ACE) Aromatase Cholecystokinin Receptor TSH Receptor Estrogen Receptor/ERR GHSR Glucocorticoid Receptor GNRH Receptor Mineralocorticoid Receptor Opioid Receptor PGD synthase PGE synthase Progesterone Receptor Thyroid Hormone Receptor
Epigenetics

AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase MicroRNA PARP PKC Protein Arginine Deiminase Methionine Adenosyltransferase (MAT) Sirtuin JAK
GPCR/G Protein

5-HT Receptor Adenosine Receptor Adenylate Cyclase (AC) Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR TSH Receptor Neuropeptide Y Receptor Dopamine Receptor EBI2/GPR183 Endothelin Receptor Formyl peptide receptor (FPR) GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPR109A GPR119 GPR139 GPR27 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR Melanocortin Receptor Melatonin Receptor mGluR Neurokinin Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor PKG Prostaglandin Receptor Protease-Activated Receptor (PAR) Apelin Receptor (APJ) Ras GPR88 Free Fatty Acid Receptor E3 Ligase Ligand-Linker Conjugates RGS GPR4 Secretin Receptor Mas-related G-protein-coupled Receptor (MRGPR) GPR35 GPR52 MCHR1 (GPR24) Leukotriene Receptor GLP Receptor Somatostatin Receptor Arrestin Platelet-activating Factor Receptor (PAFR) Mas-related G-protein-coupled Receptor (MRGPR) Kisspeptin Receptor G Protein-coupled Receptor Kinase (GRK) G protein-coupled Bile Acid Receptor 1 Succinate Receptor 1 Protease Activated Receptor (PAR) Vasopressin Receptor

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Thrombin

Thrombin相关产品（16）

货号	产品名	中文名称	产品描述
SJ-BP0343	Protamine sulfate	硫酸鲑鱼精蛋白	Protamine sulfate 是一个阳性离子肽，具有抗肝素活性，可以中和肝素的抗凝血作用，增强脂质介导的基因转移。
SJ-MN0056	Heparin sodium	肝素钠	Heparin sodium 是一种抗凝剂，可与抗凝血酶 III (ATIII) 可逆地结合，大大加快了 ATIII 使凝血酶因子 IIa 和 Xa 失活的速度。Heparin sodium 显著抑制外泌体-细胞相互作用。
SJ-BP0042	Enoxaparin sodium	依诺肝素钠	Enoxaparin sodium 是一种低分子量的合成肝素。作为一种抗凝剂/抗血栓剂，Enoxaparin sodium 的作用机制与 heparin 相似，同时它表现出更高的抗因子 Xa 与抗因子 IIa 活性的比率。Enoxaparin sodium 还具有抗炎特性，可抑制单核细胞与肿瘤坏死因子 α 或脂多糖激活的内皮细胞的粘附。与普通 heparin 相比，Enoxaparin sodium 可降低骨质疏松症和肝素诱导的血小板减少症的发生率。
SJ-MX0842	Dabigatran (BIBR 953)	达比加群	Dabigatran (BIBR 953)是一种口服可逆的，竞争性的、非肽类直接凝血酶 (thrombin) 抑制剂，无细胞试验中IC50为9.3 nM。Dabigatran (BIBR 953) 也抑制凝血酶诱导的血小板聚集 (IC50=10 nM)。
SJ-BP0057	Bivalirudin		Bivalirudin，一种肽类抗凝剂，是直接凝血酶 (thrombin) 抑制剂，可在侵入性心脏病，特别是在经皮冠状动脉介入中用于抗凝。
SJ-MX1086	NQ301		NQ301是一种抗血栓剂; 可抑制胶原蛋白激发的兔血小板聚集，IC50值为10 mg/mL。
SJ-MN0302	Argatroban	阿加曲班	Argatroban (MD-805) 是凝血酶选择性抑制剂。
SJ-MX2789	Dabigatran etexilate	达比加群酯	Dabigatran etexilate (BIBR 1048) is a reversible and selective, direct thrombin inhibitor (DTI) with Ki value of 4.5 nM. Dabigatran selectively and reversibly inhibits human thrombin (Ki = 4.5 nM) as well as thrombin-induced platelet aggregation (IC50 = 10 nM), while showing no inhibitory effect on other platelet-stimulating agents. Dabigatran displays concentration-dependent anticoagulant effects in various species in vitro.
SJ-MX2819	Edoxaban (DU-176)	依度沙班	Edoxaban(DU-176b;DU176;Lixiana;Savaysa)是一种有效的，直接作用的，选择性的，口服生物利用的Xa因子抑制剂，用作抗凝血药物。它抑制因子Xa, Ki值为0.561 nM，比凝血酶和FIXa选择性高10000倍。Edoxaban作为直接因子Xa抑制剂。
SJ-MX2789A	Dabigatran etexilate mesylate	甲磺酸达比加群酯	Dabigatran Etexilate mesylate (BIBR-1048; BIBR 1048MS) is the prodrug of dabigatran which is a potent and nonpeptidic small molecule that specifically and reversibly inhibits both free and clot-bound thrombin by binding to the active site of the thrombin molecule. Dabigatran (also known as IBR 953) is a potent nonpeptide thrombin inhibitor with an IC50 of 9.3 nM in a cell-free assay. Dabigatran is designed to be converted into an orally active prodrug BIBR 1048 due to its highly polar, zwitterionic nature and poor oral absorption. Dabigatran inhibits thrombin in a competitive fashion.
SJ-MX2944	Edoxaban tosylate monohydrate		Edoxaban tosylate monohydrate 是一种具有口服活性、高效、选择性和直接的 Factor Xa (FXa) 抑制剂，对人游离 FXa 和凝血酶原酶的 Ki 值分别为 0.561 nM 和 2.98 nM。Edoxaban tosylate monohydrate 的选择性是其他凝血蛋白酶的 10000 倍以上。Edoxaban tosylate monohydrate 可用于预防血栓栓塞性疾病的研究。
SJ-MN0302A	Argatroban monohydrate	阿加曲班一水合物	Agatroban is a potent and competitive thrombin inhibitor (Ki = 19 nM) that displays anticoagulant activity. Active in vivo.
SJ-BP0057A	Bivalirudin TFA	三氟醋酸比伐卢定	Bivalirudin TFA 是20个氨基多肽，可逆地抑制凝血酶。
SJ-MX3417	AEBSF hydrochloride		AEBSF hydrochloride 是一种特异性的、不可逆的丝氨酸蛋白酶抑制剂。抑制蛋白酶，如凝乳蛋白酶，激肽酶，纤溶酶，凝血酶和胰蛋白酶。一种稳定，无毒，更好溶的PMSF替代品。
SJ-MN0056B	Heparin	肝素	Heparin 是硫酸粘多糖，是注射抗凝剂，是负电荷密度最高的生物分子。Heparin 显著抑制外泌体-细胞相互作用。
SJ-MN0056A	Heparin Lithium salt	肝素锂	Heparin Lithium salt 是一种抗凝剂，可与抗凝血酶III (ATIII) 可逆地结合。Heparin Lithium salt 显著抑制外泌体-细胞相互作用。