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| 货号 | 产品名 | 中文名称 | 产品描述 |
|---|---|---|---|
| SJ-MN0056 | Heparin sodium | 肝素钠 | Heparin sodium 是一种抗凝剂，可与抗凝血酶III (ATIII) 可逆地结合，大大加快了ATIII使凝血酶因子IIa 和 Xa 失活的速度。Heparin sodium 显著抑制外泌体-细胞相互作用。 |
| SJ-MX0842 | Dabigatran (BIBR 953) | 达比加群 |
Dabigatran (BIBR 953)是一种口服可逆的，竞争性的、非肽类直接凝血酶 (thrombin) 抑制剂，无细胞试验中IC50为9.3 nM。Dabigatran (BIBR 953) 也抑制凝血酶诱导的血小板聚集 (IC50=10 nM)。 |
| SJ-MX2819 | Edoxaban (DU-176) | 依度沙班 | Edoxaban (also known as DU-176b; DU176; Lixiana; Savaysa) is a potent, direct-acting, selective, orally bioavailable factor Xa inhibitor used as an anticoagulant drug. It inhibits factor Xa with a Ki of 0.561 nM, >10 000-fold selectivity over thrombin and FIXa. Edoxaban acts as a direct factor Xa inhibitor. |
| SJ-MX2944 | Edoxaban tosylate monohydrate | Edoxaban tosylate monohydrate (DU-176b; DU-176; trade name Lixiana), the tosylate salt of edoxaban which is a marketed anticoagulant drug, is a potent, selective, orally bioavailable and direct factor Xa inhibitor with potential anti-coagulant activity. It inhibits Factor Xa with a Ki of 0.561 nM, and exhibits >10 000-fold selectivity over thrombin and FIXa. | |
| SJ-MX3417 | AEBSF hydrochloride |
AEBSF hydrochloride 是一种特异性的、不可逆的丝氨酸蛋白酶抑制剂。抑制蛋白酶，如凝乳蛋白酶，激肽酶，纤溶酶，凝血酶和胰蛋白酶。一种稳定，无毒，更好溶的PMSF替代品。 |
|
| SJ-MX1086 | NQ301 | NQ301是一种抗血栓剂; 可抑制胶原蛋白激发的兔血小板聚集，IC50值为10 mg/mL。 | |
| SJ-MN0302 | Argatroban | 阿加曲班 | Argatroban (MD-805) 是凝血酶选择性抑制剂。 |
| SJ-MN0302A | Argatroban monohydrate | 阿加曲班一水合物 | Agatroban is a potent and competitive thrombin inhibitor (Ki = 19 nM) that displays anticoagulant activity. Active in vivo. |
| SJ-BP0042 | Enoxaparin sodium | 依诺肝素钠 |
Enoxaparin sodium是一种低分子量的合成肝素。 作为一种抗凝剂/抗血栓剂，Enoxaparin sodium的作用机制与heparin相似，尽管它表现出更高的抗因子 Xa 与抗因子 IIa 活性的比率。Enoxaparin sodium还具有抗炎特性，可抑制单核细胞与肿瘤坏死因子 α 或脂多糖激活的内皮细胞的粘附。 与普通heparin相比，Enoxaparin sodium的使用与骨质疏松症和肝素诱导的血小板减少症的发生率降低有关。 |
| SJ-MX2789 | Dabigatran etexilate | 达比加群酯 | Dabigatran etexilate (BIBR 1048) is a reversible and selective, direct thrombin inhibitor (DTI) with Ki value of 4.5 nM. Dabigatran selectively and reversibly inhibits human thrombin (Ki = 4.5 nM) as well as thrombin-induced platelet aggregation (IC50 = 10 nM), while showing no inhibitory effect on other platelet-stimulating agents. Dabigatran displays concentration-dependent anticoagulant effects in various species in vitro. |
| SJ-MX2789A | Dabigatran etexilate mesylate | 甲磺酸达比加群酯 | Dabigatran Etexilate mesylate (BIBR-1048; BIBR 1048MS) is the prodrug of dabigatran which is a potent and nonpeptidic small molecule that specifically and reversibly inhibits both free and clot-bound thrombin by binding to the active site of the thrombin molecule. Dabigatran (also known as IBR 953) is a potent nonpeptide thrombin inhibitor with an IC50 of 9.3 nM in a cell-free assay. Dabigatran is designed to be converted into an orally active prodrug BIBR 1048 due to its highly polar, zwitterionic nature and poor oral absorption. Dabigatran inhibits thrombin in a competitive fashion. |
| SJ-BP0057A | Bivalirudin TFA | 三氟醋酸比伐卢定 | Bivalirudin TFA 是20个氨基多肽，可逆地抑制凝血酶。 |
| SJ-BP0057 | Bivalirudin | Bivalirudin，一种肽类抗凝剂，是直接凝血酶 (thrombin) 抑制剂，可在侵入性心脏病，特别是在经皮冠状动脉介入中用于抗凝。 | |
| SJ-MN0056B | Heparin | 肝素 | |
| SJ-MN0056A | Heparin Lithium salt | 肝素锂 |
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