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Anti-infection

Antibiotic Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HCV Protease HIV HIV Integrase HIV Protease HSV Influenza Virus Orthopoxvirus Parasite TMV Reverse Transcriptase RSV SARS-CoV Virus Protease
Apoptosis

Apoptosis Bcl-2 Family Caspase c-Myc Ferroptosis FKBP IAP Family MDM-2/p53 PKD Necroptosis Pyroptosis RIP kinase Thymidylate Synthase TNF Receptor TRADD Cuproptosis
Autophagy

Autophagy FKBP LRRK2 Mitophagy OGA ULK
Cell Cycle/DNA Damage

Antifolate APC ATM/ATR Aurora Kinase BMI-1 Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA/RNA Synthesis DNA-PK Early 2 Factor (E2F) Eukaryotic Initiation Factor (eIF) GAK G-quadruplex HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 DNA Stain Nucleoside Antimetabolite/Analog Nur77 p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 Cyclin G-associated Kinase (GAK) ROCK ATF6 Haspin Kinase Sirtuin SRPK PDI Telomerase TOPK Topoisomerase Wee1
Cytoskeletal Signaling

Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK ROCK
Endocrinology/Hormones

Adrenergic Receptor Androgen Receptor Angiotensin-converting Enzyme (ACE) Aromatase Cholecystokinin Receptor TSH Receptor Estrogen Receptor/ERR GHSR Glucocorticoid Receptor GNRH Receptor Mineralocorticoid Receptor Opioid Receptor PGD synthase PGE synthase Progesterone Receptor Thyroid Hormone Receptor
Epigenetics

AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase MicroRNA PARP PKC Protein Arginine Deiminase Methionine Adenosyltransferase (MAT) Sirtuin JAK
GPCR/G Protein

5-HT Receptor Adenosine Receptor Adenylate Cyclase (AC) Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR TSH Receptor Neuropeptide Y Receptor Dopamine Receptor EBI2/GPR183 Endothelin Receptor Formyl peptide receptor (FPR) GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPR109A GPR119 GPR139 GPR27 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR Melanocortin Receptor Melatonin Receptor mGluR Neurokinin Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor PKG Prostaglandin Receptor Protease-Activated Receptor (PAR) Apelin Receptor (APJ) Ras GPR88 Free Fatty Acid Receptor E3 Ligase Ligand-Linker Conjugates RGS GPR4 Secretin Receptor Mas-related G-protein-coupled Receptor (MRGPR) GPR35 GPR52 MCHR1 (GPR24) Leukotriene Receptor GLP Receptor Somatostatin Receptor Arrestin Platelet-activating Factor Receptor (PAFR) Mas-related G-protein-coupled Receptor (MRGPR) Kisspeptin Receptor G Protein-coupled Receptor Kinase (GRK) G protein-coupled Bile Acid Receptor 1 Succinate Receptor 1 Protease Activated Receptor (PAR) Vasopressin Receptor

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Liver X Receptor (LXR)

Liver X Receptor (LXR)相关产品（13）

货号	产品名	中文名称	产品描述
SJ-MN0429	Saikosaponin A	柴胡皂苷 A	Saikosaponin A 是一种三萜皂苷，是药用植物银柴胡中的主要活性成分，可上调 LXRα 的表达，具有有效抗炎、免疫调节和抗菌活性。
SJ-MX2433	RGX-104 hydrochloride		RGX-104 hydrochloride 是一种小分子 LXR 激动剂，通过 ApoE 基因的转录激活调节先天免疫。
SJ-MX1378	LXR-623 (WAY-252623)		LXR-623是可以渗透血脑屏障的 LXRα部分激动剂和 LXRβ完全激动剂，IC50 分别为24 nM 和 179 nM。
SJ-MN0314	(20S)-Protopanaxatriol	20 (S)-原人参三醇	(20S)-Protopanaxatriol 是人参皂苷的代谢物，具有神经保护活性，它是糖皮质激素受体GR和雌激素受体ERbeta的功能性配体，具有广泛的抗癌活性，可调节内皮细胞功能。
SJ-MX3546	SR9243		SR9243 is a potent , cell-permeable and selective LXR inverse agonist. SR9243 kills cancer cells by inhibiting lipid production and the Warburg effect. It induces cell death in multiple types of cancer and does not cause the side effects that have derailed previous attempts to target these processes.
SJ-MN0777	Yamogenin	雅姆皂甙元	Neodiosgenin is bioactive compound.
SJ-MX3864	AZ876		AZ-876 is a novel, potent high-affinity agonist of Liver X Receptor (LXR) with Ki values of 0.007 μM and 0.011 μM for human LXRα and LXRβ respectively. AZ876 protects against pathological cardiac hypertrophy and fibrosis without lipogenic side effects.
SJ-MX3932	SR9238		SR9238 is a selective inverse agonist of LXRα and LXRβ with IC50 values of 214 and 43 nM, respectively.
SJ-MX3981	Abequolixron		Abequolixron (SB742881; RG104; SB-742881) is a novel potent and orally bioavailable liver-X nuclear hormone receptor-beta (LXR) agonist with potential immunomodulating and anticancer activities. It modulates innate immunity via transcriptional activation of the ApoE gene.
SJ-MX4617	27-Hydroxycholesterol	27-羟基胆固醇	27-Hydroxycholesterol (27-HC) is an endogenous oxysterol with multiple biological functions, including activity as a selective estrogen receptor modulator (SERM) (a mixed, tissue-specific agonist-antagonist of the estrogen receptor (ER)) and as an agonist of the liver X receptor (LXR).
SJ-MX0712	T0901317		TT0901317 是一种有效的，选择性的性肝 X 受体 (LXR)和FXR激动剂，对 LXRα 和FXR的EC50分别约为20 nM和5 μM。T0901317 是 RORα 和 RORγ 的双重反向激动剂，对应的Ki值分别为132 nM和51 nM。T0901317 可显着抑制细胞增殖并诱导凋亡 (apoptosis)，并抑制低密度脂蛋白 (LDL) 受体缺失小鼠动脉粥样硬化的发展。
SJ-MX0753	GW3965 hydrochloride		GW3965 hydrochloride 是一种有效的，选择性肝 X 受体 (LXR) 激动剂，作用于hLXRα和hLXRβ，无细胞试验中EC50分别为190和30 nM。
SJ-MX4017	GSK2033		GSK2033 是一种 LXR 拮抗剂，对于 LXRα和 LXRβ的 pIC50 值分别为 7 和 7.4。