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Anti-infection

Antibiotic Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HCV Protease HIV HIV Integrase HIV Protease HSV Influenza Virus Orthopoxvirus Parasite TMV Reverse Transcriptase RSV SARS-CoV Virus Protease
Apoptosis

Apoptosis Bcl-2 Family Caspase c-Myc Ferroptosis FKBP IAP Family MDM-2/p53 PKD Necroptosis Pyroptosis RIP kinase Thymidylate Synthase TNF Receptor TRADD
Autophagy

Autophagy FKBP LRRK2 Mitophagy OGA ULK
Cell Cycle/DNA Damage

Antifolate APC ATM/ATR Aurora Kinase BMI-1 Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA/RNA Synthesis DNA-PK Early 2 Factor (E2F) Eukaryotic Initiation Factor (eIF) GAK G-quadruplex HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 DNA Stain Nucleoside Antimetabolite/Analog Nur77 p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 Cyclin G-associated Kinase (GAK) Nucleoside Antimetabolite/AnalogOrthopoxvirus ROCK ATF6 Haspin Kinase Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeletal Signaling

Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK ROCK
Endocrinology/Hormones

Adrenergic Receptor Androgen Receptor Angiotensin-converting Enzyme (ACE) Aromatase Cholecystokinin Receptor TSH Receptor Estrogen Receptor/ERR GHSR Glucocorticoid Receptor GNRH Receptor Mineralocorticoid Receptor Opioid Receptor PGD synthase PGE synthase Progesterone Receptor Thyroid Hormone Receptor
Epigenetics

AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain FTO HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase MicroRNA PARP PKC Protein Arginine Deiminase Methionine Adenosyltransferase (MAT) Sirtuin
GPCR/G Protein

5-HT Receptor Adenosine Receptor Adenylate Cyclase (AC) Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR TSH Receptor Neuropeptide Y Receptor Dopamine Receptor EBI2/GPR183 Endothelin Receptor Formyl peptide receptor (FPR) GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR27 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR Melanocortin Receptor Melatonin Receptor mGluR Neurokinin Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor PKG Prostaglandin Receptor Protease-Activated Receptor (PAR) Apelin Receptor (APJ) Ras GPR88 Free Fatty Acid Receptor E3 Ligase Ligand-Linker Conjugates RGS GPR4 Secretin Receptor Mas-related G-protein-coupled Receptor (MRGPR) GPR35 GPR52 MCHR1 (GPR24) Leukotriene Receptor GLP Receptor Somatostatin Receptor Vasopressin Receptor

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Factor Xa

Factor Xa相关产品（9）

货号	产品名	中文名称	产品描述
SJ-MN0056	Heparin sodium	肝素钠	Heparin sodium 是一种抗凝剂，可与抗凝血酶III (ATIII) 可逆地结合，大大加快了ATIII使凝血酶因子IIa 和 Xa 失活的速度。Heparin sodium 显著抑制外泌体-细胞相互作用。
SJ-MX0427	Rivaroxaban	利伐沙班；利伐塞班	Rivaroxaban (BAY 59-7939)是一种凝血因子 Xa (FXa)的直接抑制剂，无细胞试验中Ki和IC50分别为0.4 nM和0.7 nM。
SJ-MX0923	Apixaban	阿哌沙班	Apixaban (BMS-562247-01) 是一种高度选择性，口服可逆的凝血因子 Xa (Factor Xa) 抑制剂，抑制人和兔凝血因子 Xa 的 Ki 值分别为 0.08 nM 和 0.17 nM。Apixaban 可以用于各种血栓栓塞疾病的相关研究。
SJ-MX2743	Betrixaban (PRT054021)	贝曲西班	Betrixaban (trade name Bevyxxa; formerly PRT054021; MK-4448; PRT-021; MLN-1021 etc.) is a highly potent, selective, and orally bioavailalbe anticoagulant drug which acts as a direct factor Xa inhibitor.
SJ-MX2819	Edoxaban (DU-176)	依度沙班	Edoxaban (also known as DU-176b; DU176; Lixiana; Savaysa) is a potent, direct-acting, selective, orally bioavailable factor Xa inhibitor used as an anticoagulant drug. It inhibits factor Xa with a Ki of 0.561 nM, >10 000-fold selectivity over thrombin and FIXa. Edoxaban acts as a direct factor Xa inhibitor.
SJ-MX2944	Edoxaban tosylate monohydrate		Edoxaban tosylate monohydrate (DU-176b; DU-176; trade name Lixiana), the tosylate salt of edoxaban which is a marketed anticoagulant drug, is a potent, selective, orally bioavailable and direct factor Xa inhibitor with potential anti-coagulant activity. It inhibits Factor Xa with a Ki of 0.561 nM, and exhibits >10 000-fold selectivity over thrombin and FIXa.
SJ-MX2423	Fondaparinux sodium	磺达肝癸钠	Fondaparinux sodium 是一种抗凝血酶依赖性的 factor Xa 抑制剂。
SJ-BP0042	Enoxaparin sodium	依诺肝素钠	Enoxaparin sodium是一种低分子量的合成肝素。作为一种抗凝剂/抗血栓剂，Enoxaparin sodium的作用机制与heparin相似，尽管它表现出更高的抗因子 Xa 与抗因子 IIa 活性的比率。Enoxaparin sodium还具有抗炎特性，可抑制单核细胞与肿瘤坏死因子 α 或脂多糖激活的内皮细胞的粘附。与普通heparin相比，Enoxaparin sodium的使用与骨质疏松症和肝素诱导的血小板减少症的发生率降低有关。
SJ-MX2614	Gabexate mesylate	甲磺酸加贝酯	Gabexate mesylate 是非抗原的丝氨酸蛋白酶抑制剂。它抑制plasma kallikrein、thrombin、plasmin和 factor Xa的Ki分别是0.2 μM, 0.97 μM, 1.6 μM and 8.5 μM。Gabexate mesylate 对凝血酶的凝血活性有抗凝血作用。它通过抑制NF-kappaB和激活蛋白-1的激活来抑制脂多糖诱导的单核细胞TNF-α的产生。它能轻微抑制SARS-CoV-2 S驱动的宿主细胞进入肺细胞。