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| 货号 | 产品名 | 中文名称 | 产品描述 |
|---|---|---|---|
| SJ-MX3426 | Castanospermine | 亚胺糖栗树精胺 | Castanospermine is a potent inhibitor of α- and β-glucosidases. Exhibits antiviral properties. Inhibits HIV infectivity and thyroglobulin secretion. Displays antitumor and antiangiogenic activity. Also inhibits protein glycosylation. |
| SJ-MX3752 | LTI-291 | LTI-291 is a CNS-penetrant and allosteric glucocerebrosidase (Gcase) activator that has the potential for treatment of Parkinson's disease (PD). | |
| SJ-MX2568 | Conduritol B epoxide | Conduritol B epoxide (CBE) is an irreversible inhibitor of glucocerebrosidase, also known as acid β-glucosidase, glucosylceramidase, GBA, or GBA1 (IC50 = 9 μM). Inhibition of this lysosomal glucosidase results in the accumulation of glucocerebroside without affecting cell viability, lysosomal enzyme release, or the activity of intracellular enzymes. It also does not inhibit non-lysosomal glucosylceramidase or cytosolic β-glucosidase. | |
| SJ-MN0652 | 4'，5-Dihydroxyflavone | 4'，5-Dihydroxyflavone 是大豆 LOX-1/α-glucosidase 的抑制剂，其对大豆 LOX-1 的 Ki 值为102.6 μM，对酵母 α-glucosidase 的 IC50 值为 66 μM。 | |
| SJ-MX2693 | Ambroxol hydrochloride | 盐酸氨溴索 | Ambroxol hydrochloride (NA-872 hydrochloride) is a sodium channel blocker and mucolytic agent with antioxidant, anti-viral and anti-inflammatory properties. Inhibits tetrodotoxin (TTX)-resistant channels more potently than TTX-sensitive subtypes (IC50 values for tonic block are 35.2 and 111.5 μM respectively). More recently, it has been shown that Ambroxol induces a modest level neuron regrowth in mice with optic nerve lesions. |
| SJ-MN1203 | Voglibose | 伏格列波糖 | Voglibose是valiolamine的衍生物，能很好的抑制α-葡萄糖苷酶，可作用于高血糖症等。 |
| SJ-MN1353 | Rebaudioside A | 莱苞迪甙A | Rebaudioside A是一个甜菊醇糖苷，α-glucosidase抑制剂，IC50是35.01 µg/mL。 |
| SJ-MN0528 | Butyl isobutyl phthalate | Butyl isobutyl phthalate 可以从海带的根状茎中分离得到。Butyl isobutyl phthalate 是一种非竞争性 α-葡萄糖苷酶 (α-glucosidase) 抑制剂，IC50 值为 38 μM。Butyl isobutyl phthalate 具有降血糖作用，可用于糖尿病相关的研究。 | |
| SJ-MN0550 | Acarbose | 阿卡波糖 | Acarbose (BAY g 5421)，降糖药，是一种具有口服活性α-葡萄糖苷酶 (alpha-glucosidase) 抑制剂 (IC50=11 nM)。Acarbose 能增强磺脲类药物或胰岛素的降血糖作用。 |
| SJ-MN0552 | Oroxin A | Oroxin A 是 Oroxylum indicum（L.）Kurz (紫薇科) 种子提取物 (OISE) 的主要成分。Oroxin A 是 PPARγ的部分激动剂，可激活 PPARγ转录。Oroxin A 通过对接 PPARγ的蛋白配体结合区域起到激活作用。Oroxin A 对α-葡萄糖苷酶有抑制活性，具有抗氧化能力。Oroxin A 具有可用于癌症研究。 | |
| SJ-MN0717 | Hexylresorcinol | 4-己基间苯二酚 |
Hexylresorcinol (4-Hexylresorcinol) 是在植物中发现的一种天然化合物，具有抗菌、驱虫、防腐和抗肿瘤活性。Hexylresorcinol 可诱导鳞癌细胞凋亡 (apoptosis)。Hexylresorcinol 是一种可逆、非竞争性的 α-葡萄糖苷酶 (α-glucosidase) 抑制剂。Hexylresorcinol 具有抗 DNA 氧化损伤的保护作用。Hexylresorcinol 是蘑菇酪氨酸酶 (mushroom tyrosinase) 的有效抑制剂，对mono-phenolase的IC50值为1.24 μM，对di-phenolase的IC50值为0.85 μM。 |
| SJ-MX2693A | Ambroxol | 氨溴索 | Ambroxol is a metabolite of Bromhexine that stimulates mucociliary action and clears the air passages in the respiratory tract. It is usually administered as the hydrochloride. |
| SJ-MN0825 | Cedryl acetate | 乙酸柏木酯 | Cedryl acetate is a tricyclic sesquiterpene extracted from the plant Psidium caudatum. Cedryl acetate shows α-glucosidase inhibitory activity. |
| SJ-MN0529 | 1-Deoxynojirimycin (Duvoglustat) | 1-脱氧野尻霉素 | 1-Deoxynojirimycin (Duvoglustat) 是一种口服有效的α-葡萄糖苷酶 (α-glucosidase) 抑制剂。1-Deoxynojirimycin 抑制餐后血糖，预防糖尿病。1-Deoxynojirimycin 具有降血糖、减肥和抗病毒的作用。 |
| SJ-MN0529A | 1-Deoxynojirimycin hydrochloride | 去氧野艽霉素盐酸盐 |
1-Deoxynojirimycin hydrochloride (Duvoglustat hydrochloride) 是一种口服有效的 α-葡萄糖苷酶 (α-glucosidase) 抑制剂。1-Deoxynojirimycin hydrochloride 抑制餐后血糖，预防糖尿病。1-Deoxynojirimycin hydrochloride 具有降血糖、减肥和抗病毒的作用。 |
| SJ-MN1146 | 3,4-Dicaffeoylquinic acid | 异绿原酸B | 3,4-Dicaffeoylquinic acid 是天然分离的，具有抗氧化，DNA 保护，神经保护和肝保护特性。3,4-Dicaffeoylquinic acid 具有凋亡介导的细胞毒性和α-葡萄糖苷酶 (α-glucosidase) 抑制作用。3,4-Dicaffeoylquinic acid 具有独特的抗病毒作用机制，即通过增加 TRAIL 来提高病毒清除率。 |
| SJ-MN0998 | Fucoidan | 岩藻多糖；褐藻糖胶 |
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