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Glucocorticoid Receptor

Glucocorticoid Receptor相关产品(37)
货号 产品名 中文名称 产品描述
SJ-MH0026 Mifepristone 米非司酮;美服培酮

Mifepristone (RU486)是黄体酮受体 (PR) 和糖皮质激素受体 (GR) 拮抗剂,体外实验中的 IC50 值分别为0.2 nM 和2.6 nM。Mifepristone 可促进细胞自噬和细胞凋亡,降低 Bcl-2 表达水平而增加Beclin1水平,并伴随Bcl-2和Beclin1之间的相互作用减弱。

SJ-MH0016 Beclomethasone 倍氯米松 Beclometasone (Beclomethasone) 是一种糖皮质激素受体 (glucocorticoid receptor) 激动剂。
SJ-MH0033 Triamcinolone acetonide

Triamcinolone acetonide 是一种更有效的triamcinolone类型,其有效性约为prednisone的 8 倍。

SJ-MH0019B Prednisolone disodium phosphate 泼尼松龙21-磷酸二钠 Prednisolone sodium phosphate is a water soluble form of prednisolone and a glucocorticoid with anti-inflammatory and immunomodulating properties. It is used to treat a variety of inflammatory and autoimmune conditions and some cancers. It is the active metabolite of the drug prednisone and is used especially in patients with liver failure, as these individuals are unable to metabolize prednisone into active prednisolone.
SJ-MH0032 Flunisolide 氟尼缩松 Flunisolide is a synthetic corticosteroid with anti-inflammatory and antiallergic properties.
SJ-MH0040 Betamethasone dipropionate 二丙酸倍他米松 Betamethasone dipropionate (Alphatrex; BetaVal; Diprolene; SCH-11460; SCH11460; Diprolene AF; Diprosone; Luxiq; Betamethasone 17,21-dipropionate) is a synthetic glucocorticoid steroid with anti-inflammatory and immunosuppressive activities. It is approved as a topical cream, ointment, lotion or gel (Diprolene) to treat itching and other minor skin conditions such as eczema.
SJ-MH0041 Betamethasone valerate Betamethasone Valerate (BV; BET; Betoid; Valison; 9α-Fluo; Valisone; Bedermin; Betneval; Beta-Val; Bextasol; Dermosol; Stanoval) is a moderately potent and commonly used glucocorticoid steroid with anti-inflammatory and immunosuppressive activities. Betamethasone valerate is approved as an anti-inflammatory corticosteroid for topical applications.
SJ-MX2479 Beclometasone dipropionate 二丙酸倍氯米松

Beclometasone dipropionate 是 Beclometasone 的前体药物,是口服有效的糖皮质激素受体激动剂。Beclometasone dipropionate 通过糖皮质激素受体发挥作用,抑制炎症和过度增殖。Beclometasone dipropionate 可用于哮喘研究。

SJ-MH0068 Desonide Desonide is a low-potency topical corticosteroid.
SJ-MH0072 Loteprednol Etabonate Loteprednol Etabonate is an anti-inflammatory corticosteroid used in optometry and ophthalmology.
SJ-MH0077 Fluocinonide 氟轻松 Fluocinonide is a potent glucocorticoid/corticosteroid that has been approved for use as a topical anti-inflammatory drug for the treatment of skin disorders such as seborrhoeic dermatitis and eczema.
SJ-MH0080 Deflazacort 地夫可特 Deflazacort (ML-458; ML458; DL-458-IT, L-5458) is a potent glucocorticoid drug approved for use as an anti-inflammatory and immunosuppressant.
SJ-MH0081 Triamcinolone 曲安西龙 Triamcinolone (BRN2341955), a long-acting synthetic corticosteroid, is an approved glucocorticoid medication with anti-inflammatory activities. Itcan be applied topically for the management of various disorders such as eczema, psoriasis, arthritis, allergies, ulcerative colitis, lupus, etc.
SJ-MH0015 Ciclesonide 环索奈德 Ciclesonide (RPR251526) 是一种具有强效抗炎活性的糖皮质激素,可用于哮喘研究。
SJ-MX2124 AL 082D06 AL 082D06 是一种选择性的非甾体类糖皮质激素受体 (GR) 拮抗剂,Ki 为 210 nM。
SJ-MN0314 (20S)-Protopanaxatriol 20 (S)-原人参三醇

(20S)-Protopanaxatriol 是人参皂苷的代谢物,具有神经保护活性,它是糖皮质激素受体GR和雌激素受体ERbeta的功能性配体,具有广泛的抗癌活性,可调节内皮细胞功能。

SJ-MN0320 Corticosterone 皮质酮

Corticosterone是一种肾上腺皮质类固醇,作为盐皮质激素和糖皮质激素具有适度但显著的活性。

SJ-MH0019A Prednisolone 泼尼松龙 Prednisolone 是一种有效的,口服活性的皮质类固醇和糖皮质激素。Prednisolone 的抗炎活性约为氢化可的松的四倍,同时减少了盐和水的保留。Prednisolone 可用于眼部抗炎研究。
SJ-MN0322 Prednisone 强的松 Prednisone 是一种人工合成的皮质类固醇剂,是特别有效的免疫抑制剂的化合物。
SJ-MH0012 Fluticasone propionate 丙酸氟替卡松 Fluticasone propionate 是一种有效的局部抗炎激素,一种选择性的糖皮质激素受体 (glucocorticoid receptor) 激动剂,绝对亲和力 KD 为 0.5 nM。Fluticasone propionate 在其他甾体受体上几乎没有活性。具有抗病毒活性。